Atomoxetine — a practical guide for people with ADHD

If you or someone you care for is considering atomoxetine, here’s a plain‑spoken summary of what to expect. Atomoxetine (brand name Strattera in some countries) is a nonstimulant medicine used mainly for ADHD. It works differently from stimulants and has its own set of benefits, timing, and safety checks.

How atomoxetine works and who it helps

Atomoxetine blocks the reuptake of norepinephrine, which can improve attention and reduce impulsivity for many people with ADHD. Because it’s not a stimulant, it has lower risk for misuse and doesn’t usually cause the same jitteriness or sleep problems stimulants can. It’s often chosen when stimulants aren’t tolerated, there’s a history of substance misuse, or when a daily nonstimulant plan fits better with other health issues.

Expect slow buildup. Some people notice improvements in 2–4 weeks, but full benefits often take 6–8 weeks. That means patience and regular check‑ins with your prescriber are important.

Dosage, side effects, and safety tips

Dosing varies by age and weight. For adults a common target dose is 40–100 mg per day, but your doctor will start lower and adjust. Children’s doses are usually weight‑based. Never change dose without talking to the prescriber.

Common side effects include stomach upset, decreased appetite, sleep changes, dry mouth, and dizziness. Less common but important issues are increases in heart rate or blood pressure, and rare liver problems. There’s also a small risk of increased suicidal thoughts in children and adolescents — this needs quick attention if mood or behavior changes appear.

Atomoxetine is processed by CYP2D6 in the liver. If you take strong CYP2D6 inhibitors (for example, fluoxetine or paroxetine), atomoxetine levels can rise and side effects can increase. Tell your doctor about all prescription drugs, antidepressants, and even some herbal supplements. Avoid mixing atomoxetine with MAO inhibitors.

Before starting, your prescriber should check heart rate and blood pressure and ask about mood, liver disease, and other meds. If you have liver problems or are a known slow CYP2D6 metabolizer, your doctor may choose a different dose or a different drug.

Buying medication online? Only use licensed pharmacies and always get a prescription from a qualified clinician. Watch out for sites that promise quick fixes or don’t require a prescription — those are risky. If you need help finding safe online sources, reach out to a trusted pharmacist or your clinic.

If side effects are bothersome or you spot mood changes, sleep loss, or fast heart rate, call your prescriber. Atomoxetine can help a lot for the right person, but like all meds it needs the right dose, follow‑up, and a clear plan for safety.

Want more help? Use the Contact page to reach us or talk directly with your healthcare team before making changes to your treatment.